The following has evaluated to null or missing:
==> mostrarTituloH2 [in template "20102#20129#105831" at line 4, column 40]
----
Tip: If the failing expression is known to legally refer to something that's sometimes null or missing, either specify a default value like myOptionalVar!myDefault, or use <#if myOptionalVar??>when-present<#else>when-missing</#if>. (These only cover the last step of the expression; to cover the whole expression, use parenthesis: (myOptionalVar.foo)!myDefault, (myOptionalVar.foo)??
----
----
FTL stack trace ("~" means nesting-related):
- Failed at: #assign hayH2 = getterUtil.getBoolean... [in template "20102#20129#105831" at line 4, column 1]
----
1<#assign title = .vars['reserved-article-title'].getData()>
2<div class="containerInterior">
3<#assign hayH1 = getterUtil.getBoolean(MostrarTituloH1.getData())>
4<#assign hayH2 = getterUtil.getBoolean(mostrarTituloH2.getData())>
5
6<#if hayH1>
7 <h1 aria-level="1" role="heading" id="titulo">${layout.getName(locale)}</h1>
8</#if>
9<#if hayH2>
10
11 <#if TituloContenido.getData()?? && TituloContenido.getData() != "">
12 <#assign contenido = TituloContenido.getData()>
13 <#else>
14 <#assign contenido = title>
15 </#if>
16
17 <#if hayH1>
18 <p id="subtitulo"
19 aria-level="2"
20 role="heading"
21 style="
22 color: #007f33 !important;
23 font-size: 45px;
24 font-family: 'IberPangea Medium', sans-serif;
25 line-height: 45px;
26 margin-top: .75em;
27 margin-bottom: .9em;">
28 ${contenido}
29 </p>
30 <#else>
31 <p id="subtitulo"
32 style="
33 color: #007f33 !important;
34 font-size: 45px;
35 font-family: 'IberPangea Medium', sans-serif;
36 line-height: 45px;
37 margin-top: .75em;
38 margin-bottom: .9em;">
39 ${contenido}
40 </p>
41 </#if>
42
43</#if>
44
45<#if getterUtil.getBoolean(MostrarCategorias.getData())>
46
47
48
49 <#assign journalArticleId = .vars['reserved-article-id'].data>
50 <#assign journalArticleLocalService = serviceLocator.findService("com.liferay.journal.service.JournalArticleLocalService")>
51
52 <#assign assetCategoryPropertyLocalService = serviceLocator.findService("com.liferay.asset.category.property.service.AssetCategoryPropertyLocalService") />
53
54 <#assign article = journalArticleLocalService.getArticle(groupId, .vars['reserved-article-id'].data) />
55 <#assign assetEntryLocalService = serviceLocator.findService("com.liferay.asset.kernel.service.AssetEntryLocalService")>
56 <#assign asset = assetEntryLocalService.getEntry('com.liferay.journal.model.JournalArticle', article.resourcePrimKey) >
57 <#assign layoutLocalService = serviceLocator.findService("com.liferay.portal.kernel.service.LayoutLocalService") />
58
59 <p class="tag-categorias">
60
61 <#list asset.getCategories() as category>
62
63
64
65 <#if assetCategoryPropertyLocalService.fetchCategoryProperty(category.getCategoryId(), "friendlyURL")??>
66
67 <#assign categoryFriendly = '/tag/' + assetCategoryPropertyLocalService.fetchCategoryProperty(category.getCategoryId(), "friendlyURL").getValue() />
68
69 <#if layoutLocalService.fetchLayoutByFriendlyURL(groupId, false, categoryFriendly)??>
70 <#assign categoryLayout = layoutLocalService.fetchLayoutByFriendlyURL(groupId, false, categoryFriendly) />
71 <#assign categoryLayoutURL = portalUtil.getLayoutFullURL(categoryLayout, themeDisplay) />
72
73 <a class="tag-categoria" href="${categoryLayoutURL}">${category.getTitle(locale)?cap_first}</a>
74
75 <#else>
76 <a class="tag-categoria" href="/tag/#">${category.getTitle(locale)?cap_first}</a>
77
78 </#if>
79 </#if>
80
81
82
83
84 </#list>
85
86 </p>
87
88</#if>
89<div id="contenidoEntradilla">${DescripcionDetalleContenido.getData()}</div>
90
91
92<#if ContenidoWebcofl.getSiblings()?has_content>
93 <#list ContenidoWebcofl.getSiblings() as cur_ContenidoWebcofl>
94 <#assign
95 webContentData = jsonFactoryUtil.createJSONObject(cur_ContenidoWebcofl.getData())
96 />
97
98 <#if webContentData?length gt 5>
99 <@liferay_asset["asset-display"]
100 className = webContentData.className
101 classPK = webContentData.classPK?number
102 />
103
104 </#if>
105
106
107 </#list>
108</#if>
109</div>
110<@liferay_util["html-top"]>
111<style>
112 #decPagination div.containerInterior p#subtitulo {
113 font-family: "Iberpangea Medium";
114 font-size: 45px;
115 line-height: 45px;
116 color: #007F33;
117 margin-bottom: 20px;
118 }
119
120
121 div.contenidoCentrado div.contenidoInterior div.containerInterior p.tag-categorias a.tag-categoria:focus{
122 outline: 2px solid rgba(0, 0, 0, 0.7) !important;
123 }
124 p.tag-categorias > .tag-categoria {
125 width: auto !important;
126 max-width: inherit !important;
127 }
128
129 div.faldon h2 {
130 width: 100%;
131 float: left;
132 font-size: 1.26em;
133 font-family: IberPangeaText Light, sans-serif;
134 margin-bottom: 2em;
135 border-bottom: 1px solid #e0e0e0;
136 padding-bottom: .8em;
137 color: #427314 !important;
138
139 line-height: 1.35em;
140 margin-top: .75em;
141 }
142 .contenidoInterior div.faldon h2+ul li:before {
143 margin: .15em 0 0 -1.75em;
144 font-size: 1em;
145 }
146 .cursiva_texto {
147 font-style: italic;
148 }
149 .contenidoInterior h1 {
150 font-family: 'IberPangea', sans-serif !important;
151 font-size: 32px !important;
152 border: none !important;
153 line-height: 36px !important;
154 letter-spacing: 0px !important;
155 color: #00402A !important;
156 padding-left: 0em !important;
157 margin-bottom: 14px !important;
158 }
159 p span.table a.enlace-actualidad[href*="/tag/"],
160 p span.table a.enlace-actualidad[href*="/label/"],
161 p.tag-categorias a.tag-categoria[href*="/tag/"],
162 p.tag-categorias a.tag-categoria[href*="/label/"]{
163 line-height: 23px !important;
164 }
165 .contenidoInterior #contenidoEntradilla p.entradilla {
166 font-family: IberPangeaText, sans-serif !important;
167 font-size: 17px !important;
168 line-height: 23px !important;
169 font-weight: 700;
170 color: #615D5A !important;
171 margin-top: 2em;
172 }
173
174 .contenidoInterior h2#subtitulo{
175 font-family: 'IberPangea Medium', sans-serif !important;
176 margin-bottom: 0.4em;
177 }
178 #decPagination div.containerInterior{
179 max-width:980px;
180 margin:0 auto 25px;
181 }
182 #decPagination div.containerInterior h1#titulo{
183 font-family:"Iberpangea Medium";
184 font-size:32px;
185 line-height:36px;
186 color:#00402A;
187 text-transform:none;
188 border-left:none;
189 margin-top:20px;
190 }
191 #decPagination div.containerInterior h2#subtitulo{
192 font-family:"Iberpangea Medium";
193 font-size:45px;
194 line-height:45px;
195 color:#007F33;
196 margin-bottom:20px;
197 }
198 #decPagination div.containerInterior p.tag-categorias{
199 margin-bottom:30px !important;
200 }
201 #decPagination div.containerInterior p.tag-categorias a.tag-categoria{
202 margin-right:20px;
203 color:#00402A;
204 }
205 #decPagination div.containerInterior div#contenidoEntradilla p.entradilla{
206 font-family:"IberpangeaText";
207 font-size:20px ;
208 line-height:26px;
209 color:#615D5A;
210 }
211 @media all and (max-width:500px){
212 #decPagination div.containerInterior h1#titulo{
213 font-size:26px;
214 line-height:36px;
215 }
216 #decPagination div.containerInterior h2#subtitulo{
217 font-size:35px;
218 line-height:35px;
219 margin-bottom:20px;
220 }
221 #decPagination div.containerInterior div#contenidoEntradilla p.entradilla{
222 font-family:"IberpangeaText Bold";
223 font-size:16px ;
224 line-height:24px;
225 }
226 }
227 @media screen and (max-width: 47.95em) {
228 .contenidoInterior h1 {
229 font-size: 26px !important;
230 }
231 .contenidoInterior h2#subtitulo{
232 font-size: 35px;
233 line-height: 35px;
234 color: #007F33 !important;
235 margin-bottom: 1em;
236 }
237 .contenidoInterior #contenidoEntradilla p.entradilla {
238 margin-top: 0.8em;
239 }
240 .contenidoInterior #contenidoEntradilla p.entradilla {
241 line-height: 24px !important;
242 }
243 }
244
245
246</style>
247</@>
It has been calculated that in 2020, a total of 1.7 megabytes of data were created per second per person in the world, and it was processed thanks to techniques like big data. Although it seems incredible, the quantity of information contained in living organisms is not far behind. A person's DNA contains around 750 megabytes of information, just under a gigabyte, and extremely powerful computers and algorithms are needed to process this biological information. This is where bioinformatics comes in.
Bioinformatics, for example, has been crucial in the fight against the SARS-CoV-2 virus that causes COVID-19. In particular, computer analysis has made it possible to decipher the molecular structure of virus proteins in a way never before possible, allowing effective vaccines to be developed in record time to halt the spread of the virus.
WHAT DOES BIOINFORMATICS STUDY
According to the National Human Genome Research Institute (NHGRI), bioinformatics is a subdiscipline of biology and computing that serves to acquire, store, analyse and disseminate biological data, mostly DNA and amino acid sequences. For example, to study how normal cell activity is altered during an illness, it is necessary to combine data relating to numerous compounds and interpret the changes. This is especially true for proteins, the building blocks of life.
In the beginning, the term bioinformatics did not have the same meaning, as it was applied to the theoretical study of biological processes. However, advances in computing and data processing have made it possible to sequence more and more proteins automatically, culminating in a milestone: the sequencing of the human genome in 2004.
OBJECTIVES OF BIOINFORMATICS
These days, the most important part of bioinformatics is the analysis and interpretation of biological molecules, a process called computational biology. One might say, in fact, that bioinformatics is the linguistic side of genetics. The fundamental objectives are to identify genes and proteins, determine their functions, establish evolutionary relationships and predict their conformation.
Bioinformatics uses computing techniques that are applied in other fields, such as artificial intelligence, and which include pattern recognition, machine learning algorithms and data visualisation. It is also the current basis of biotechnology thanks to which it will be possible to develop more efficient drugs, genetic treatments and even progress in the fight against climate change, which makes the bioinformaticians a digital profile of the future.
WHAT DO BIOINFORMATICIANS DO
Bioinformatic scientists have to analyse large amounts of data at the molecular and genomic level. As part of their work, they must develop the necessary software to obtain these data and create new algorithms to interpret and adapt them to the needs of the project they are working on. They also create graphical visualisations of these data and their results.
In June 2021, a team of bioinformaticians presented the results which, through artificial intelligence, had allowed them to predict the structures of almost all the proteins made by the human body, more than 350,000 of them. This breakthrough is one of the most important in recent years and has enabled an enormous leap forward in our understanding of the body and the development of new drugs to treat diseases.
APPLICATIONS OF BIOINFORMATICS
Bioinformatics is a multidisciplinary field used in many life sciences, so it has numerous applications. Let's take a look at some of them:
Medicine
It has led to advances in personalised medicine, adapting treatments to each person's genetics.
Pharmacology
It has had a fundamental role in pharmaceutical research, particularly in combatting infectious diseases, and in developing vaccines.
Genetics
It is applied to gene therapy, particularly in illnesses caused by individual genes that have been affected or inherited. Likewise, the comparison of genomic data adds to our knowledge of the evolutional history of life on Earth.
Agriculture
The use of proteomics, metabolomics and genetics allows stronger crops to be developed that are more resistant to drought and insect pests.
Livestock
It is used to sequence the genome of farm animals, prevent diseases and to give them more resistence and a better quality of life.
Wastes
It allows the DNA sequencing of bacteria and microbes to identify and evaluate their use in wastewater clean-up, radioactive waste disposal or plastics recycling.